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The most well-known are breast cancer gene 1 BRCA1 and breast cancer gene 2 BRCA2 both of which significantly increase the risk of both breast and ovarian cancer. The type of tissue where your breast cancer arises determines how the cancer behaves and what treatments are most effective. Award Winner The Karma Foundation Logo Kreatif Parts of the breast where cancer begins include. . This type of cancer forms in the lining of a milk duct within your breast. Ductal carcinoma is the most common type of breast cancer. If you have a strong family history of breast cancer or other cancers your doctor may recommend a blood test to help identify specific mutations in BRCA or other genes that are being passed.